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Biology punishment

- What did the microbiologist give his biologist girlfriend for her birthday?
Designer genes, of course. You were expecting flowers?

- An English major taking his biology exam referred to a microtome as an ‘itsy bitsy book.’ More »

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New study: Metagenomics gets a gut feel

I couldn’t resist the pun in the title of this post: Metagenomics gets a gut feel. The newly released study behind it, which is having considerable play in the media and on the internet, is the first genetic catalog of the microbes (bacteria, fungi, others) that make up the microbiome (ecosystem) of the human gut. It’s more than a catalog of the wee beasties; it’s also a complete sequencing of the genomes from the most common of the inhabitants. This is the first such massive metagenomics project, where the idea is to analyze and compare the genomes of all the participants in the microbiome. More »

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Posted in Impact: DNA Decoding | Tagged , , , , , , , , | Leave a comment

Found: Another molecule needed at the origin of life

Very often important science is constructed by a myriad of small advances in knowledge. This is almost certainly going to be true for answering one of the big questions in biology: “How did life on Earth originate?”

It’s been known for a long time that it probably originated where there was a concentrated mixture of organic compounds. (Just because they’re called organic, doesn’t mean all such compounds come from living things – it simply means they’re carbon-based.) Out of that mixture, which is usually labeled the primal soup came the chemical processes that eventually put together some of the available organic compounds until they became ‘self-assembling’ – a process that would automatically repeat following natural chemical reactions (or pathways). For this to happen, it was necessary that short organic compounds (‘short’ meaning just a few elements such as carbon, oxygen, and hydrogen in a simple chain) into even longer organic compounds – polymers. Eventually within the ‘primal soup’ polymers were created that at least partly resembled RNA (Ribonucleic Acid), which is now the ‘messenger’ of the DNA code but archaically almost certainly developed before DNA. More »

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For real: A new way to produce electricity

It’s not every day that a new way to produce electricity is discovered…although it does seem there is a multitude of approaches. This one involves carbon nanotubes, those jacks-of-all-trades in the nanotech business, nanometer sized tubes of pure carbon. (In this case, think of them as ‘wires’ one-hundred thousandth of the thickness of human hair.) The team of scientists at MIT (Massachusetts Institute of Technology, USA) began working with nanotubes and thermal waves – waves of heat energy – that they sent down the nanotubes like current through wires. To their surprise, what they also got was a relatively large voltage electrical current generated by the thermopower wave. More »

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Species Loss: It is statistics but not a game

Most biologists will tell you that the Earth is losing species faster than it is replacing them. One prominent biologist, Simon Stuart, chair of the Species Survival Commission for the International Union for the Conservation of Nature (IUCN), has said about two new reports coming out in March (2010):

“Measuring the rate at which new species evolve is difficult, but there’s no question that the current extinction rates are faster than [replacement]; I think it’s inevitable.”

The IUCN created shock waves with its major assessment of the world’s biodiversity in 2004, which calculated that the rate of extinction had reached 100-1,000 times that suggested by the fossil records before humans.

No formal calculations have been published since, but conservationists agree the rate of loss has increased since then, and Stuart said it was possible that the dramatic predictions of experts like the renowned Harvard biologist E O Wilson, that the rate of loss could reach 10,000 times the background rate in two decades, could be correct.

“All the evidence is he’s right,” said Stuart. “Some people claim it already is that … things can only have deteriorated because of the drivers of the losses, such as habitat loss and climate change, all getting worse. But we haven’t measured extinction rates again since 2004 and because our current estimates contain a tenfold range there has to be a very big deterioration or improvement to pick up a change.”

[Source: The Guardian]

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New: Single molecule sensor array

If there is a spectrum that can be detected by sensors, from very small to very big, then the sensor array built by engineers at the Massachusetts Institute of Technology (MIT, Cambridge, USA) can stake a claim for the very smallest – a single molecule. The array uses carbon nanotubes, which are rapidly becoming the Swiss Army Knife of nanotechnology, to detect the molecule of hydrogen peroxide on as small a surface as a single cell. You may ask, why hydrogen peroxide? More »

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Finally(?)…artificially making blood stem cells in quantity

This story begins with an insight: The cells of a vascular system (veins, arteries, capillaries) – called endothelial cells – do more than make up the tissue that transports blood; they also play a role in maintaining blood (hematopoietic) stem cells by producing novel stem-cell-growth factors. A research team at the Ansary Stem Cell Institute at Weill Cornell Medical Collage (New York, USA) discovered that by culturing stem cells together with adult endothelial cells, the stem cells would continue propagating and remain alive far longer than with any other technique – weeks, instead of days. This opens a door to producing stem cells in quantity. More »

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Climate Change: Madness in their methane?

A few years ago the whole ‘cow farts are global climate threat’ thing seemed more than a bit overblown. (Cow and other farts being mostly methane, dontcha know.) It became difficult to mention methane in connection with global warming without raising images of bovine herds worldwide in a massive chorus of postprandial flatulence. Besides, CO2 is the real bête noir of climate. Methane would be if there was a lot more of it in the atmosphere, but its percentage is small (< 1%). It’s a more effective greenhouse gas than CO2. It can make lots of ‘interesting’ atmospheric combinations at the molecular level, and its concentration in the atmosphere can change more rapidly than CO2. That last point, rapid change in concentration, may be the parameter of concern for the new study that (revising figures from a 2005 study) indicates there may be more methane outgassing from the Siberian shelf than thought. More »

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Update: Chinese space station

The China National Space Administration has announced plans to launch the first module of a space station in 2011. The station, named Tiangong “Heavenly Place”, will consist of several modules, the first being Tiangong-1. The first module, weighing 8.5 tons and launched aboard a modified China’s Long March 2F rocket, will be unmanned. Over the next two years, three additional modules on Shenzhou spacecraft, each with two or three people, will dock with Tiangong-1. The final configuration will be smaller than the Soviet station, Mir.

Tiangong-1 was scheduled to launch by the end of 2010, but was delayed for technical reasons. It represents the culmination of a larger project, Project 921, started by the Chinese space program in 1992.

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Follow-up: Maybe Chicxulub didn’t do it

Not enough evidence. It’s one of the most important, and difficult to evaluate, criticisms in science. In his blog “In terra veritas” post 41 Angry Scientists, Bryan (a geologist) takes on the Science article The Chicxulub Asteroid Impact and Mass Extinction at the Cretaceous-Paleogene Boundary. He has two main complaints: The ‘panel of 41’ that authored the report is presenting essentially rehash of information loosely accepted since 1980, and in any case, there is insufficient evidence to draw such a hard-edged conclusion for any mass extinction event. More »

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Looking at the strange face of antimatter

Scarcely three weeks ago, it was reported that the Relativistic Heavy Ion Collider (RHIC) at the Brookhaven National Laboratory had achieved the all time (laboratory) high temperature record of 4 trillion degrees Centigrade. [SciTechStory: Taking the temperature of the Big Bang + milliseconds] The significance was that in colliding atoms of gold and producing such high temperatures they discovered that instead of the expected gas, a plasma (liquid, a veritable soup) of particles was created. Now, in another study completed at the same facility with the RHIC STAR detector, an international team of scientist is reporting some of the first particle discoveries. In this case, it’s antimatter, the heaviest known antinucleus, and the first containing an anti-strange quark. ? You ask. It’s a new frontier of physics, they’ll answer. More »

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Reading the brain for motor control – without implants

It’s been decades since neuroscience began the search for ways ‘read the brain’ so that people can move, communicate, and respond when their physical body can no longer do so. Just about every year there are advances, and announcements, of this and that device, which can interpret the brain’s neuron electrical pulses to perform something like control a computer, activate a robotic limb, or produce artificial speech. More »

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Science panel: Chicxulub did it

Sometimes ‘the facts’ discovered by science answer questions by themselves, but much of the time facts are used for competing hypotheses. Sometimes more facts settle the issue of which hypothesis better fits the facts, but like as not, the ‘better fit’ is a matter of interpretation. If the issue at hand is important enough, scientists will sometimes round up a group of specialists (a panel of experts) and try to assess the evidence (facts) for a consensus conclusion. This is the case for global warming. It is also the case for Chicxulub and a mass extinction of half the life on Earth. More »

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Life on Mars, if it exists, is below the surface

Is there life on Mars? We don’t know yet. If there is, it isn’t very big. In fact, if there’s (still) any life at all, it will be bacteria or something even more primitive and small. Whatever there is, it’s also not likely to be on the surface. That’s not because of the cold; it’s the radiation – specifically the ultraviolet (UV) radiation. That’s part of the results of an Italian study, led by researcher Giuseppe Galletta, University of Padua (Italy), which simulated Martian surface conditions and their effects on bacteria populations. More »

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A black hole of good news – bad news

Tucson, Arizona – Astronomers at the University of Arizona have dubbed a new observation – the “chaos cloud.” Discovered by the Kepler Space Telescope on March 1, the swirling, 10 million kilometer wide cosmic cloud has been likened to nothing ever seen before.

Although measurements are preliminary, astronomers said the cloud would sweep through Earth at approximately 09:15:30.1 GMT on June 14, 2013.

“The good news is that this finding confirms several leading-edge concepts in theoretical physics,” announced Dr. Adelbert de Casselum, a Tucson based astrophysicist with close ties to NASA, ESA, and JIRI but not affiliated with the University of Arizona. More »

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A different kind of lens for time

In the sense that a lens refracts (bends) light, you could say that using galaxies as a lens is reasonable – if the scale of measurement is nothing less than the age of the universe. It never hurts to have confirmation (in science and a lot of other things). While we know from various studies that the age of the universe is about 13.75 billion years (+/- 170 million), to have this confirmed by another method is…comforting, in a cosmological way. The method in this case is kind of breathtaking. More »

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Can culture change the genome?

Almost from the beginning of our knowledge of genetics, it’s been asked, “Can the way we (humans) live change our genetics?” These days this is much the same as asking if culture can change the genome. It’s actually a relatively old question.

The question got its biggest boost from one who is now a boogeyman for biology, Jean-Baptiste Lamarck (1744-1829). Lamarckism is the idea that an organism can pass on to its offspring characteristics that it acquired during its lifetime. This is sometimes called Lamarckian inheritance or soft inheritance and was a popular idea until Darwin, Mendel, and modern genetics put various nails into the Lamarckian coffin. (Lamarckian ideas, zombie like, resurfaced very politically as Lysenkoism for a while in Soviet Russia.) The mechanics of genes, DNA, and reproduction as we now understand them rule out the ‘genetic codification’ (ad hoc, as it were,) of such fleeting characteristics as appeared in an individual. This is also interpreted to mean that cultural influences, say, whether you drank a lot of milk or not, are not part of the genetic patterns. More »

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Posted in Impact: Genetic Modification | Tagged , , , , , , , , , , , , | 1 Comment

Oh please, “skinput”

Research work from a collaboration between Microsoft and Carnegie Mellon University (USA) has resulted in an armband that can sense taps on human skin (the arm in this case) and uses sound vibration detection (an acoustic biosensor) to determine the location for a kind of crude ‘button’ or ‘keyboard’ arrangement. It also uses a picoprojector (like a tiny LED projector) to display the buttons on the skin. They call it skinput.

Obviously the advantage here is that nothing needs to be implanted under the skin to create an arm control panel. Of course, the external wristband is subject to the usual problems of a wristwatch – banging it against something, losing it, breaking the clasp. Although technology marches on, it can always use some tweaking.

Is anybody asking why ‘skinput’ is needed? (Be careful what you scorn – in a decade or two skinput might seem perfectly routine.)

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Technology predictions so awful, they’re good

Making predictions about future technology, or even the impact of current technology is tempting fate. That is to say, you’re fated to be wrong, much of the time…at best. I should know; it’s what this blog does a lot. However, I’ve always liked the definition of an expert, attributed to Niels Bohr or Werner Heisenberg that goes, “An expert is someone who knows some of the worst mistakes in his field and how to avoid them.” I’m working on the how to avoid them part.

However, there’s falling off a chair, and there’s falling down a mountain. There are degrees of bad in making predictions. Some predictions are so bad, they are outstanding. Farhad Manjoo, one of the best IT/Technology bloggers around (over at Slate), has latched on to something that’s been going around the internet for a little while. It’s a 1995 Newsweek column by Clifford Stoll titled The Internet? Bah!. That gives you a clue. Manjoo’s post That Whole Internet Thing’s Not Going To Work Out summarizes Stoll’s article quite well, but reading the original doesn’t hurt. More »

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Update: More Moon water

Last year, in a flurry of “NASA Bombs Moon!” stories, the NASA LCROSS (Lunar Crater Observation and Sensing Satellite) project deliberately crashed into a deeply shadowed crater to kick up dust and test its contents – looking particularly for water. They found it. [SciTechStory: On the Moon or elsewhere follow the water] The quantities found were relatively small, but any water at all on the Moon was something of a breakthrough. At that point the stock of ‘Moon Base’ ideas went up, because water is such a versatile substance (like humans need it, and it can make rocket fuel). Now there’s more – more water that is, as confirmed by the Chandrayaan-1, India’s spacecraft that was sent to the Moon about the same time as LCROSS. Among other things, before it conked out, Chandrayaan-1 used its on-board Mini-SAR instrument (mini-Synthetic Aperture Radar, a piece of NASA equipment) to scan the Moon’s north pole craters for water. More »

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