Tag Archives: aging

Stem cell injection improves aging cells in mice

“The provocative findings urge further research,” said Dr. Niedernhofer, one of the senior investigators on a University of Pittsburgh (USA) stem cell project. The context is injecting stem cells from young mice into very old mice and mice with progeria, a disease that causes rapid aging. As described in Nature Communications [03 January 2012, Open [...]
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Guanfacine: A possible drug to improve memory in old age

As you get old, you start to forget things. True. Not that you couldn’t forget things when you’re younger and distracted; but as you get older, perhaps you’re more easily distracted. Why would that be? There are many lines of research into the loss of memory capacity as we age. One such line is conducted [...]
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Putting the impact of dementia in perspective

What constitutes a major disease? Percentage of population affected, certainly. Global prevalence, yes. Severity of effects, yes. Difficulty of treatment, perhaps. I wrestled with this question in thinking about creating a category of medical research that will have great impact on human life, an Impact Area. There are so many diseases. Unless you’re a medical [...]
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Extending life with diet or insulin has trade-offs

Over the last decade or so, two of the most promising avenues of research in gerontology (the study of aging) and the search for means of extending human life have been on the effects of restricting diet and the activity of the hormone insulin. Numerous studies have shown that caloric restriction (not starvation, but a [...]
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New study: Genetic variations associated with aging

Sometimes the shortest distance to new knowledge is a lot of repetitious work – like analyzing 500,000 genetic variations across the entire human genome. Researchers at King’s College London (UK), Leicester University (UK), and the University of Groningen (Netherlands) were on the trail of locating genes associated with aging. This is part of the (perhaps) [...]
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What if most people lived to 100?

It’s more than possible. In the not very distant future, most people will live to be 100 years old. That possibility…should make people pause. First off: Is it true? Second: If true, when might it happen? Third: What does that mean, for a lot of things? Almost a third of the “impact areas” listed here [...]
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Can we stimulate repair of old muscles?

Yes, we probably can stimulate more repair of muscle cells in older people. Berkeley — A study led by researchers at the University of California, Berkeley, has identified critical biochemical pathways linked to the aging of human muscle. By manipulating these pathways, the researchers were able to turn back the clock on old human muscle, [...]
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