Tag Archives: double-helix

Hoogsteen base pairs: An alternate structure in DNA

Reverse Hoogsteen base pairing…..Wikipedia Commons I know some of my biases. One of them is knee-jerk skepticism about taking little-tested scientific results and blowing them up to “…a cure for cancer” or “…revolutionize the electronics industry.” However, like most people I also have a bias to be curious about interesting, if somewhat unusual scientific findings. [...]
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Quantum entanglement helps keep DNA together

Once in a while science produces theoretical work that has tantalizing possibilities but also raises a strong skeptical response. This is another way of saying that a theory has a certain amount of plausibility but is without experimental evidence. Such is the case with a theory proposed by Elisabeth Rieper and colleagues at the National [...]
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In the helix grooves – how proteins find the DNA

This is one of those stories in science that is a little difficult to visualize. Let’s start with the shape of a DNA chromosome – a double helix, right? It looks a bit like a spiral staircase, with the rails being nucleotides and the steps being the bases. Now imagine descending a spiral staircase looking [...]
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Forming the double helix – learning more about hybridization

Our knowledge of cell biology, of genetics, indeed of life itself has centered on the role of DNA. Yet since the structure of DNA was first elucidated by Watson and Crick more than fifty years ago, we are still attempting to explain the intricate processes involving DNA. One of these processes, DNA hybridization, is the [...]
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