Tag Archives: gene expression

Histones: DNA packaging and much more

DNA winds around histones….Credit: Max Planck Society Most everybody knows that DNA is the carrier of the genetic code, the instructions for how life reproduces, grows, and maintains. Cell biologists have long known that DNA comes with a very complex packaging material, proteins called histones, which help the 2 meter (6 foot) strand of DNA [...]
Posted in Impact: DNA Decoding | Also tagged , , , , , , , | 1 Comment

Fascinating: Many of us have genes from Neanderthals

One way or another many human beings carry a percentage of their DNA inherited from Neanderthal man. This has been suspected for some time (not only in comedy routines); now there is genetic data to back it up. An international team of scientists coordinated at the Max Planck Institute of Evolutionary Anthropology (Leipzig, Germany) and [...]
Posted in Impact: DNA Decoding | Also tagged , , , , , , , , , | Comments closed

A new layer of genetic information: DNA sub-code

To some it sounds like something out of a spy story – sub-codes within the genetic code. Ah the hidden code; Dan Brown would be proud of the discovery. The actual discovery is perhaps not so thrilling, but potentially much more important than novelistic entertainment. Two researchers, Professor Yves Barral (ETH Zurich, Switzerland), and Dr. [...]
Posted in News: DNA Decoding | Also tagged , , , , , , , , | Leave a comment

Disease linked genes have environmental factors too

Within the human body there are few diseases that aren’t influenced by some kind of environmental factors (stress, obesity, smoking, lack of sleep). Put another way, even diseases that have a genetic link (cancer, heart disease, diabetes) are not fully explained by genetics – environmental factors also play a role. Teasing apart the ‘who does [...]
Posted in News: Cell Biology | Also tagged , , , , , | Leave a comment

There’s more to gene expression than biochemistry

At a guess, ninety-nine percent of biologists’ attention to DNA and gene expression is based on biochemistry. That’s good, since the biochemistry is obviously important and difficult enough to analyze. However, there is something else – it’s called physics. Cells, cell components, and DNA all exist in the physical world and therefore are also affected [...]
Posted in News: Cell Biology | Also tagged , , , , , , , | Leave a comment

Formerly, one brain cancer…now it’s four

One of the things that makes cancer so difficult to ‘cure’ is that it has so many forms. Perhaps most difficult of all, as scientists are learning, are cancers such as the most common and usually fatal brain cancer glioblastoma multiforme (GBM). As a new study at the University of North Carolina (Chapel Hill, USA) [...]
Posted in News: Major Disease Cures | Also tagged , , , | Leave a comment

Stapling peptides to drug the undruggable

Turning specific genes on and off is something Nature does routinely. Not so for scientists. In particular, a class of proteins that control whether certain genes are activated or not, so called transcription factors, have been considered unreachable. Because of their complex folded configurations, transcription proteins are highly resistant to modification and have been considered [...]
Posted in News: Major Disease Cures | Also tagged , , , , , | Leave a comment