Tag Archives: genome

Stem cell epigenomic development mapped

Completing the map of the human genome, back in 2000 and 2003, was a monumental task and a milestone on the road to understanding our genetics. Here’s another milestone: A map that shows in detail how the human genome is modified during embryonic development. Just completed and published by a team of researchers from the [...]
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Brain cancer genome sequenced

The cost of sequencing a human genome has come down, way down; and the value of doing it is going up. Here’s a very good example: scientists at the University of California Los Angeles (USA) recently completed the sequencing of the DNA from a type of brain cancer cell line, a glioblastoma known as U87. [...]
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Common diseases: Rare gene mutations are important

Recall seeing a headline like this: “Gene discovered that causes cancer”? Over the past decade or so such headlines have been frequent. The advent of genome-wide association studies (GWAS), looking through the whole human genome to find variant genes, has uncovered literally thousands of relationships between common gene mutations and various forms of cancer and [...]
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Corn (maize) genome sequenced

Sequencing of this or that animal or plant genome is becoming fairly routine; but this one – sequencing of the maize genome – is something of a milestone. Maize, or as the Yanks say ‘corn’ is one of the world’s great cash crops. Maize has been subject to selective breeding for centuries, but armed with [...]
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Evolution seen through 10K vertebrate genomes

Some are calling it a ‘genome zoo.’ Others say it will be the world’s greatest menagerie of vertebrate genomes. Yes, you could say that about the launch of the Genome 10K Community of Scientists (G10KCOS), but this massive project – in its way at least as ambitious as the famed Human Genome Project – is [...]
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Mapping human genome variations

The mapping of the human genome was a monumental achievement; however, it was always intended to be just a starting point. Where has the follow-up work gone? One area is mapping of copy number variants. Normally our (non-sex) chromosomes come in twos (humans are said to be diploid), but the machinery of DNA reproduction relatively [...]
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