Tag Archives: microbiology

The microbiome: Our life in common with microorganisms

Fifth in a series of posts inspired by ten topics in ‘Insights of the Decade’ from the December 17, 2010 special issue of Science Magazine The topics are: Inflammation, climatology, tricks of light, alien planets, the microbiome, cell development, Martian water, the DNA time machine, cosmology and epigenetics. The original articles are now behind a [...]
Posted in Impact: Cell Biology | Also tagged , , , , , , , , , , , , , , | 3 Comments

Synthetic life, as developed by Craig Venter et al

May 21, 2010: This is one of those days when one story is likely to dominate the science news. It will also be writ large in the world’s news. Craig Venter, the name has to come first, and his research team has claimed creation of the first synthetic life. It should also be a good [...]
Posted in Impact: Synthetic Biology | Also tagged , , , , , , , , | Leave a comment

Protein pathway competition regulates embryo development

One thing I’ve noticed in following scientific developments for a long time is that when something unexpected is discovered it very often adds to the complexity. Here’s a recent case in point, first, I’ll let a piece of the announcement speak for itself, and then I’ll explain the context: Until now, scientists believed these pathways [...]
Posted in Impact: Cell Biology | Also tagged , , , , , , , | Leave a comment

New study: Metagenomics gets a gut feel

I couldn’t resist the pun in the title of this post: Metagenomics gets a gut feel. The newly released study behind it, which is having considerable play in the media and on the internet, is the first genetic catalog of the microbes (bacteria, fungi, others) that make up the microbiome (ecosystem) of the human gut. [...]
Posted in Impact: DNA Decoding | Also tagged , , , , , , , | Leave a comment

Ribozymes and the origin of life

It could be called the search for the origin of life, but instead of a sweeping theory (primordial soup and lightning), microbiologists are concentrating on the many pieces that, one way or another, came together to constitute ‘life.’ Some new research from a team at the University of Colorado (Boulder, USA) points to the smallest [...]
Posted in News: Origin of Life | Also tagged , , , , , , | Leave a comment

New medical paradigm: Growing human organs in animals

The ability to manipulate genetics cuts in a number of ways. This way may sound a little strange: Take a mouse; implant human liver cells in it; watch them grow into a mouse-sized but human liver. It’s more complicated than that, but it works. There are reasons to do this. A lot of tests for [...]
Posted in News: Synthetic Biology | Also tagged , , , , , | Leave a comment

Disease linked genes have environmental factors too

Within the human body there are few diseases that aren’t influenced by some kind of environmental factors (stress, obesity, smoking, lack of sleep). Put another way, even diseases that have a genetic link (cancer, heart disease, diabetes) are not fully explained by genetics – environmental factors also play a role. Teasing apart the ‘who does [...]
Posted in News: Cell Biology | Also tagged , , , , , | Leave a comment

Four-letter codons: A new synthetic biology playground

All life (that we know of) is built from the 4 nucleotides of DNA (Adenine, Guanine, Cytosine, Thymine and in RNA Uracil instead of Thymine), which provide the code for creating 22 amino acids, which are then combined into proteins. An important part of the process is the reading of the DNA code by RNA [...]
Posted in Impact: Proteomics | Also tagged , , , , , , , | Leave a comment

Iterating toward artificial life

There’s more than one way to make a stew – but a primordial stew, the original mix of (whatever) materials from which life arose? This was a stew millions, if not hundreds of millions of years in the making. How can we recreate that evolutionary process within the ephemeral lifespan of a science laboratory? Then [...]
Posted in Impact: Synthetic Biology | Also tagged , , , , , , , , | Leave a comment

Beyond the genome: Mapping the epigenome

Given all the coverage, most people have heard about the ‘mapping of the human genome.’ It was a big project, taking many years (1990-2003) and costing about three billion dollars. Typically it was heralded as ‘one of the greatest scientific achievements of the century.’ It was that, although among those involved it was clearly a [...]
Posted in News: DNA Decoding | Also tagged , , , , , | Leave a comment

Meet the hot dot-Janus particle

One of the big research tracks for nanotechnology is the ability to control the alignment and shape of nanoparticles. Control is vital for nano-manufacturing (building something with nanoparticles) and also for many medical uses of nanotechnology. “Control” in this sense means the ability to move nanoparticles on command in any dimension with the ultimate control [...]
Posted in News: Nanotechnology | Also tagged , , | Leave a comment

More molecular medical delivery

One of the most important areas of nanotech research and development is the area of nanoscale delivery systems for drugs and genetic material. Advances occur frequently. Here’s another one: Theresa M. Reineke, associate professor of chemistry in the College of Science, and colleagues in her lab at Virginia Tech and at the University of Cincinnati [...]
Posted in News: Nanomedicine | Also tagged , , , , , | Leave a comment

Learning over time better than cramming

We are just beginning to learn how memory works at the molecular and genetic level. Observations about how memory works are now acquiring fundamental explanations. For example: A new study from the Montreal Neurological Institute and Hospital (The Neuro) of McGill University reveals that different patterns of training and learning lead to different types of [...]
Posted in News: Neuroscience | Also tagged , , , | Leave a comment

Hand-held cancer detection device

Trekkers will remember Dr. McCoy carrying a hand-held device which could instantly diagnose (and often treat) diseases. We aren’t there yet, but this development is indicative of where we’re going: University of Toronto researchers have used nanomaterials to develop a microchip sensitive enough to quickly determine the type and severity of a patient’s cancer so [...]
Posted in News: Nanomedicine | Also tagged , , , , , , | 1 Comment

Shaping DNA on demand

Scientists at the Technische Universitaet Muenchen (TUM) and Harvard University have thrown the lid off a new toolbox for building nanoscale structures out of DNA, with complex twisting and curving shapes. In the August 7 issue of the journal Science, they report a series of experiments in which they folded DNA, origami-like, into three dimensional [...]
Posted in News: Nanomedicine | Also tagged , | Leave a comment