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Tag Archives: proteomics
Proteins and quantum transition: Instant shape-shifting
Every once in a great while a piece of very interesting science comes along, quietly, until more and more people notice that not only is important but it may be right. Then scientists get into high gear and start doing more intensive experimenting. Sometimes the science press or even the popular media catch wind of [...]
Posted in Impact: Proteomics Also tagged amino acids, biochemistry, configuration, DNA, Lu, Luo, protein, protein folding, quantum folding, quantum mechanics, quantum transition Leave a comment
Reprogramming cells: The post stem cell future?
Sixth in a series of posts inspired by ten topics in ‘Insights of the Decade’ from the December 17, 2010 special issue of Science Magazine The topics are: Inflammation, climatology, tricks of light, alien planets, the microbiome, cell reprogramming, Martian water, the DNA time machine, cosmology and epigenetics. The original articles are now behind a [...]
Posted in Impact: Stem Cells Also tagged cell biology, cell reprogramming, DNA, embryonic stem cells, epigenetics, genetic modification, genetics, Gurdon, iPSC, pluripotent, stem cells, Yamanaka Leave a comment
New proteomics: Fat isn’t inactive
Most people think of fat as stuff that just sits there – like the pendulous beer belly or the not so cute love handles. Scientists too have long thought of fat…and fat cells…as simply repositories of lipids (fats), which are storehouse material for energy that can be used by the body. Recent work, however, is [...]
A new role for a key cell protein
We know from our experience, intuition, and scads of studies that the body reacts to stress – often negatively. For the most part, long term stress is harmful. There are many muscular, neurological, vascular, and digestive reactions (to name a few) that if not significantly relieved by some point, turn toward physical degeneration and disease [...]
New study: Steps toward understanding the ferritin ‘nanocage’
Proteins are the building blocks of cells, tissues, and the larger creations of life (such as humans), which makes them important. That doesn’t make them easy to understand. In fact, studies such as one about the protein ferritin, just released by researchers at Nanyang Technological University (Singapore) in the Journal of Biological Chemistry, tend to [...]
Posted in News: Proteomics Also tagged amino acid, enzyme, ferritin, nanoarchitecture, nanocage, nanoparticle, nanostructure, protein Leave a comment
Discovery: Cell protein transport and an approach to cancer
The center of this story, in more ways than one, is the Golgi apparatus (pronounced ‘goal jee’). As a crude analogy, think of the Golgi apparatus as a re-packaging operation inside of living cells. It receives packages (called vesicles, which are like tiny bubbles) of proteins from the parts of the cell where proteins are [...]
Posted in Impact: Cell Biology Also tagged cancer, cell biology, cell membrane, Golgi body, mitochondria, palmitoylation, palmostatin B, protein, RAS, transport Comments closed
Evolution treats transcription factors differently than DNA
People with reddish hair have genes for that, but what gets the job done – that is, growing reddish hair – isn’t the DNA or gene, it’s the transcription of the genes by molecules of protein, mainly RNA polymerase transcribing into messenger RNA (mRNA), which takes the designs coded in DNA and guides the production [...]
Posted in News: Proteomics Also tagged DNA, epigenetics, evolution, genes, genetics, molecular biology, protein, speciation, species, transcription, tRNA Leave a comment
New link between proteins and memory
Just as geneticists are finding that proteins play a complex and often crucial role in the expression of genes, the link between memory and proteins presents much new territory for neuroscience. That makes it exciting, for those in the field; and tantalizingly inconclusive. Work being done by Dr. Nahum Sonenberg at McGill University (Canada) has [...]
Posted in News: Neuroscience Also tagged 4E-BP2, deamidation, memory, neuroscience, proteins Leave a comment
New study: Tracking proteins that repair DNA
There are some lines of research in the development of science that in all likelihood will not have a ‘breakthrough’ – a big rush of discovery. Instead, the discovery will be piecemeal; sometimes it will be discovery in very small pieces accumulating until a hypothesis is verified. Not all tracks like this are important, but [...]
Posted in News: Proteomics Also tagged DNA, genes, genetics, proteins, repair complex, UvrA Leave a comment
Protein pathway competition regulates embryo development
One thing I’ve noticed in following scientific developments for a long time is that when something unexpected is discovered it very often adds to the complexity. Here’s a recent case in point, first, I’ll let a piece of the announcement speak for itself, and then I’ll explain the context: Until now, scientists believed these pathways [...]
Posted in Impact: Cell Biology Also tagged cell biology, DNA, enzyme, genes, MAPK, microbiology, pathways, protein Leave a comment
First time: Watching the unfolding story of proteins in living cells
Think of looking at cells in vitro (the biologists way of saying the cells are in a Petri dish or a test tube – ‘in glass’) as watching animals in a zoo. It looks relatively natural, but it isn’t. There could be differences, perhaps important differences between the way a cell behaves in vitro and [...]
Posted in News: Proteomics Also tagged Fast Relaxation Imaging, fluorescence microscopy, in vitro, in vivo, protein folding, UV Leave a comment
Four-letter codons: A new synthetic biology playground
All life (that we know of) is built from the 4 nucleotides of DNA (Adenine, Guanine, Cytosine, Thymine and in RNA Uracil instead of Thymine), which provide the code for creating 22 amino acids, which are then combined into proteins. An important part of the process is the reading of the DNA code by RNA [...]
Posted in Impact: Proteomics Also tagged codons, DNA, genetics, microbiology, nucleotides, RNA, transcription, tRNA Leave a comment
Plants, animals, and proteins between them
Horizontal movement of DNA (genes passing between species) is well-known and the basis of major research (and disagreement). Less known and much less researched is a similar sharing of proteins between species. Virtually unknown and probably under-researched is protein shared between plants and animals. New work by Wendy Peer at Purdue University (Indiana, USA) could [...]
Posted in News: Proteomics Also tagged DNA, epigenetics, genes, genetics, plants, protein Leave a comment
lincRNA: A recently discovered RNA organizes stem cell differentiation