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Tag Archives: transcription
Reversing silenced genes improves quality of induced stem cells
As has been the case for more than a decade, the promise of stem cells to create breakthroughs in cell biology and medicine has been hampered by the difficulty in obtaining sufficient quantities of high quality pluripotent stem cells (cells capable of changing into almost any other kind of cell). Human embryonic stem cells are [...]
Posted in News: Stem Cells Also tagged DNA, embryonic stem cells, gene, genetic, iPSC, molecular genetics, pluripotent, RNA, stem cells Leave a comment
Genetic pause control
Did you know that the genetic production process (gene expression) can be paused? A few years ago, most geneticists didn’t know either, and now it appears that the ability to pause genetic expression is not limited to a handful of genes (as originally thought) and may be a general capability for cells at all stages [...]
Posted in News: DNA Decoding Also tagged c-Myc, chromosome, DNA, DSIF, genes, genetics, mRNA, NELF, nucleus, polymerase enzyme, protein, stem cells Leave a comment
A new layer of genetic information: DNA sub-code
To some it sounds like something out of a spy story – sub-codes within the genetic code. Ah the hidden code; Dan Brown would be proud of the discovery. The actual discovery is perhaps not so thrilling, but potentially much more important than novelistic entertainment. Two researchers, Professor Yves Barral (ETH Zurich, Switzerland), and Dr. [...]
Posted in News: DNA Decoding Also tagged cell biology, DNA, gene expression, genetics, molecular biology, regulation, RNA, sub-code, tRNA Leave a comment
Evolution treats transcription factors differently than DNA
People with reddish hair have genes for that, but what gets the job done – that is, growing reddish hair – isn’t the DNA or gene, it’s the transcription of the genes by molecules of protein, mainly RNA polymerase transcribing into messenger RNA (mRNA), which takes the designs coded in DNA and guides the production [...]
Posted in News: Proteomics Also tagged DNA, epigenetics, evolution, genes, genetics, molecular biology, protein, proteomics, speciation, species, tRNA Leave a comment
Small RNA: New pathways for gene regulation?
Sometimes research discovers more than expected. (It could be called serendipity.) In this case, researchers from the Max Planck Institute in Berlin (Germany) were exploring the bacterium Helicobacter pylori, which is a microscopic beasty that lives in the gut of about 50% of humanity. H. pylori, as it is abbreviated, has been linked to a [...]
Posted in Impact: DNA Decoding Also tagged biochemistry, DNA, genetics, Helicobacter pylori, junk DNA, pathogen, RNA, sRNA Leave a comment
Four-letter codons: A new synthetic biology playground
All life (that we know of) is built from the 4 nucleotides of DNA (Adenine, Guanine, Cytosine, Thymine and in RNA Uracil instead of Thymine), which provide the code for creating 22 amino acids, which are then combined into proteins. An important part of the process is the reading of the DNA code by RNA [...]
Posted in Impact: Proteomics Also tagged codons, DNA, genetics, microbiology, nucleotides, proteomics, RNA, tRNA Leave a comment
A form of muscular dystrophy depends on ‘junk’ DNA